The Metro line between Benton and Monkseaton is closed for 15 days to allow for a major programme of track replacement.
The work, which forms part of the £350m Metro all change modernisation programme, will involve the replacement of ageing track and tracks beds, which are more than 60 years old.
When the line is closed a frequent replacement bus service, 900, will be operating from Four Lane Ends interchange calling at all Metro stations on the affected route.
Director of Rail and Infrastructure for Nexus, Raymond Johnstone, said: “This is our second major piece of modernisation work in North Tyneside this year. It is vital work.
“We are replacing sections of line between Benton and Monkseaton. The tracks are 50 years old and the work needs to be done now as part of our £350m Metro all change programme.
“This can only be done effectively by closing the Metro line for 15 days. We’ll be working round the clock to keep the disruption to a minimum.
“When the line is closed our customers will be provided with a frequent replacement bus service and they won’t be more than two or three stops away from linking back into the Metro system. I’d like to apologise in advance to anyone who is inconvenienced by the line closure.”
Nexus has ensured the work is carried out in the summer because passenger numbers are lower at this time of year, especially when the schools are shut for the summer break.
Tynemouth, Cullercoats and Whitley Bay Metro stations will remain open throughout the line closure and will be served by trains on the Metro line that operates from Newcastle via Wallsend.
Metro services to and from Newcastle city centre via Wallsend will continue to run to the usual frequencies, terminating at Monkseaton, with an enhanced service during peak periods.